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Cayman Vas2870; Purity- Greater Than Or Equal To 98%; Size- 1 Mg
NETA PART: | CAYM-19205-1 |
MFG.PART: | 19205-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
VAS2870 is a selective inhibitor of the NADPH oxidases.,,, Pre-incubation of rat vascular smooth muscle cells with VAS2870 abolishes platelet-derived growth factor-dependent chemotaxis without affecting cell cycle progression (IC50 = 10 µM). At low (2.8 mM), but not high (16.7 mM), concentrations of glucose, treatment with VAS2870 (20 µM) increases glucose-stimulated insulin secretion of rat pancreatic islets by 70%. It significantly reduces production of reactive oxygen species in mouse brain, rat vascular smooth muscle culture, and human umbilical vein endothelial cells.,, Treatment with VAS2870 pre- or post-ischemia is neuroprotective in mouse brain. VAS2870 inhibits vasculogenesis of mouse embryonic stem cell cultures and inhibits cell proliferation of rat hepatoma cells.,
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 30 mg/ml
- DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
- DMSO: 25 mg/ml
Shipping & Storage Information
SKU | CAYM-19205-1 |
---|---|
Supplier Part Number | 19205-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19205m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 722456-31-7 |