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Cayman Azd 3264; Purity- Greater Than Or Equal To 98%; Size- 25 M
Cayman Azd 3264; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$692.00
Your Price
$692.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-19309-25 |
MFG.PART: | 19309-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Association of Ras protein with the inner surface of the plasma membrane is required for Ras signaling activity. Farnesyl thiosalicylic acid (FTS) amide is an FTS derivative with an amide added to the carboxyl group. FTS amide inhibits the growth of PANC-1 and U87 tumor cells with IC50 values of 20 and 10 µM, respectively, a relatively higher potency compared to that of FTS (IC50s = 35 and 50 µM, respectively). Treatment of nude mice bearing either U87 glioblastoma or PANC-1 tumors with 100 mg/kg FTS amide twice daily for four days inhibits tumor growth by at least 50% of controls.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2- [[(2E,6E)- 3,7,11- trimethyl- 2,6,10- dodecatrien- 1- yl]thio]- benzamide
CAS Number
1092521-74-8
Synonyms
- FTS Amide
- Salirasib Amide
Molecular Formula
C22H31NOS
Formula Weight
357.6
Purity
≥96%
Formulation
A solution in ethanol
Solubility
- DMF: 12 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 20 mg/ml
SMILES
C\C(CC/C=C(CC/C=C(C)\C)\C)=C/CSC1=C(C(N)=O)C=CC=C1
InChi Code
InChI=1S/C22H31NOS/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-25-21-14-6-5-13-20(21)22(23)24/h5-6,9,11,13-15H,7-8,10,12,16H2,1-4H3,(H2,23,24)/b18-11+,19-15+
InChi Key
GZTMFRUGZMZCRD-CFBAGHHKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
SKU | CAYM-19309-25 |
---|---|
Supplier Part Number | 19309-25 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19309m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 25 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 1609281-86-8 |