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Cayman Zearalanone; Purity- Greater Than Or Equal To 98%; Size- 1
Cayman Zearalanone; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$49.00
Your Price
$49.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-19459-1 |
| MFG.PART: | 19459-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Endothelin-2 is a peptide vasoconstrictor and ligand for the endothelin (ET) receptors ETA and ETB (Kbs= 32.8 and 1.33 nM, respectively). It induces β-arrestin recruitment in CHO-K1 cells expressing human ETA and ETB (pD2s =8.75 and 8.55, respectively). Ex vivo, endothelin-2 induces vformal asoconstriction in isolated rat mesenteric arterial beds (ED50 = 90.8 pmol). Endothelin-2 also induces contraction of isolated rat uteri, an effect which is reversed by the ETA antagonist BQ-123 but not the ETB antagonist BQ-788 (Item No. ). Infusion of endothelin-2 restores vasoconstriction of vessels at the follicular apex of the ovarian follicle and ovulation in Amhr2cre/+Smo2 mice.
WARNING This product is not for human or veterinary use.
Technical Information
Synonyms
- ET-2 (human)
Molecular Formula
C115H160N26O32S4 • XCF3COOH
Formula Weight
2546.9
Purity
≥95%
Formulation
A lyophilized powder
Solubility
- Water: 1 mg/ml
SMILES
OC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@@]([H])(NC([C@@]([H])(NC([C@@H](NC([C@@H](NC([C@H](CC3=CNC=N3)NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@H](CC5=CC=C(C=C5)O)NC([C@H](C(C)C)NC([C@]6(NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC([C@H](CC(O)=O)NC7=O)=O)=O)=O)[H])=O)=O)=O)=O)CSSC[C@H](N)C(N[C@@H](CO)C(N[C@](C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CC8=CNC9=C8C=CC=C9)C(N[C@H]7CC(C)C)=O)=O)=O)=O)(CSSC6)[H])=O)=O)=O)=O)CC(C)C)=O)CC(O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C115H160N26O32S4.C2HF3O2/c1-11-59(9)93(113(170)132-82(115(172)173)41-64-46-120-71-27-19-17-25-68(64)71)141-114(171)94(60(10)12-2)140-105(162)81(44-91(150)151)130-99(156)75(37-57(5)6)125-103(160)79(42-65-47-118-55-121-65)128-109(166)86-52-175-174-51-69(117)95(152)133-83(48-142)108(165)138-87-53-176-177-54-88(111(168)139-92(58(7)8)112(169)131-77(39-62-29-31-66(145)32-30-62)100(157)126-76(101(158)137-86)38-61-22-14-13-15-23-61)136-97(154)73(33-34-89(146)147)123-96(153)72(28-20-21-35-116)122-104(161)80(43-90(148)149)129-98(155)74(36-56(3)4)124-102(159)78(40-63-45-119-70-26-18-16-24-67(63)70)127-106(163)84(49-143)134-107(164)85(50-144)135-110(87)167;3-2(4,5)1(6)7/h13-19,22-27,29-32,45-47,55-60,69,72-88,92-94,119-120,142-145H,11-12,20-21,28,33-44,48-54,116-117H2,1-10H3,(H,118,121)(H,122,161)(H,123,153)(H,124,159)(H,125,160)(H,126,157)(H,127,163)(H,128,166)(H,129,155)(H,130,156)(H,131,169)(H,132,170)(H,133,152)(H,134,164)(H,135,167)(H,136,154)(H,137,158)(H,138,165)(H,139,168)(H,140,162)(H,141,171)(H,146,147)(H,148,149)(H,150,151)(H,172,173);(H,6,7)/t59-,60-,69-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,92-,93-,94-;/m0./s1
InChi Key
PNYUQHKZRVJPIS-JOTLSKGISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19459-1 |
|---|---|
| Supplier Part Number | 19459-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/19459m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | IL |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 5975-78-0 |