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Cayman Phgdh-Inactive; Purity- Greater Than Or Equal To 98%; Size
Cayman Phgdh-Inactive; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$380.00
Your Price
$380.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-19717-10 |
| MFG.PART: | 19717-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
PHGDH-inactive is an inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 (Item No. 19716) and NCT-503 (Item No. 19718).1 Unlike the inhibitors, PHGDH-inactive does not inhibit PHGDH in vitro (IC50s = >57, 3.7, and 2.5 µM for PHGDH-inactive, NCT-502, and NCT-503, respectively), block serine synthesis in cells, or kill PHGDH-dependent cell lines.1 PHGDH-inactive is intended to serve as a negative control for NCT-502 and NCT-503.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(4,6-
CAS Number
1914971-16-6
Synonyms
- 3-Phosphoglycerate Dehydrogenase-inactive
Molecular Formula
C17H21N5S
Formula Weight
327.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 2 mg/mL
- DMSO: 5 mg/mL
- DMSO:PBS (pH 7.2)(1:5): 0.1 mg/mL
λmax
278, 351 nm
SMILES
S=C(N1CCN(C2=CC=NC=C2)CC1)NC3=NC(C)=CC(C)=C3
InChi Code
InChI=1S/C17H21N5S/c1-13-11-14(2)19-16(12-13)20-17(23)22-9-7-21(8-10-22)15-3-5-18-6-4-15/h3-6,11-12H,7-10H2,1-2H3,(H,19,20,23)
InChi Key
ITLPIAAGIQAGRA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19717-10 |
|---|---|
| Supplier Part Number | 19717-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/19717m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1914971-16-6 |