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Cayman Ry785; Purity- Greater Than Or Equal To 98%; Size- 500 Mic
Cayman Ry785; Purity- Greater Than Or Equal To 98%; Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$39.00
Your Price
$39.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-19813-500 |
MFG.PART: | 19813-500 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
BHPI is an antagonist of estrogen receptor α (ERα) that blocks 17β-estradiol-induced proliferation of drug-resistant breast, endometrial, and ovarian cancer cell lines at concentrations ranging from 10 to 1,000 nM. It is effective in vivo, driving tumor regression in mice bearing MCF-7 xenografts at a dose of 15 mg/kg daily. BHPI specifically inhibits ERα-dependent gene expression and protein synthesis by activating the unfolded protein response in cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one
CAS Number
56632-39-4
Molecular Formula
C21H17NO3
Formula Weight
331.4
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/ml
- DMSO: 11 mg/ml
- Ethanol: 14 mg/ml
- Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
SMILES
CC1=C(NC(C2(C3=CC=C(O)C=C3)C4=CC=C(O)C=C4)=O)C2=CC=C1
InChi Code
InChI=1S/C21H17NO3/c1-13-3-2-4-18-19(13)22-20(25)21(18,14-5-9-16(23)10-6-14)15-7-11-17(24)12-8-15/h2-12,23-24H,1H3,(H,22,25)
InChi Key
FABLAHMQSQFDHR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-19813-500 |
---|---|
Supplier Part Number | 19813-500 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19813m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1393748-80-5 |