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Cayman Chrysophanol; Purity- Greater Than Or Equal To 98%; Size-
NETA PART: | CAYM-19870-100 |
MFG.PART: | 19870-100 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Chrysophanol is an anthraquinone that has been found in R. palmatum and has diverse biological activities.,, It induces necrosis in J5 human liver cancer cells when used at concentrations of 25, 50, 75, 100, and 200 µM. Chrysophanol (5, 10, and 50 µM) reduces LPS-induced production of nitric oxide (NO) and prostaglandin E2 (PGE2; Item No. ) and inhibits LPS-induced DNA oxidation in BV-2 microglia. In vivo, chrysophanol (5 mg/kg) decreases colonic levels of IL-6 and activation of NF-κB and reduces weight loss, diarrhea, and rectal bleeding in a mouse model of colitis induced by dextran sulfate (DSS; Item No. ). Chrysophanol (0.1, 1, and 10 mg/kg) increases survival, reduces brain tissue loss, and ameliorates motor balance deficits in a mouse model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO).
WARNING This product is not for human or veterinary use.
Technical Information
- Chrysophanic Acid
- NSC 37132
- NSC 646567
- Turkey Rhubarb
- DMF: 0.5 mg/mL
- DMSO: 0.2 mg/mL
Shipping & Storage Information
SKU | CAYM-19870-100 |
---|---|
Supplier Part Number | 19870-100 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19870m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 100 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 481-74-3 |