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Cayman Sea0400; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
Cayman Sea0400; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$380.00
Your Price
$380.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-19876-10 |
MFG.PART: | 19876-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Ac-QPKK(Ac)-AMC is a fluorogenic substrate for sirtuin 1 (SIRT1), SIRT2, and SIRT3. It is selectively deacylated by SIRT1-3 over SIRT6. Upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N2-acetyl-L- glutaminyl-L- prolyl-L-lysyl- N6-acetyl-N- (4-methyl-2- oxo-2H-1-benzo pyran-7-yl)- L-lysinamide
CAS Number
1387005-23-3
Synonyms
- Ac-Gln-Pro-Lys-Lys-(Ac)-AMC
- Ac-Gln-Pro-Lys-Lys-(Ac)-7-amino-4-methylcoumarin
- p53317-320 Substrate (Ac-QPKK(Ac)-AMC)
Molecular Formula
C36H52N8O9
Formula Weight
740.9
Purity
≥98%
Emission
440-460 nm
Excitation
340-360 nm
Formulation
A solid
Solubility
- DMF: 10 mg/mL
- DMSO: 15 mg/mL
- Ethanol: Slightly Soluble
- PBS (pH 7.2): 10 mg/mL
SMILES
NCCCC[C@@H](C(N[C@H](C(NC1=CC=C(C(C)=CC(O2)=O)C2=C1)=O)CCCCNC(C)=O)=O)NC([C@@H]3CCCN3C([C@H](CCC(N)=O)NC(C)=O)=O)=O
InChi Code
InChI=1S/C36H52N8O9/c1-21-19-32(48)53-30-20-24(12-13-25(21)30)41-33(49)26(10-5-7-17-39-22(2)45)42-34(50)27(9-4-6-16-37)43-35(51)29-11-8-18-44(29)36(52)28(40-23(3)46)14-15-31(38)47/h12-13,19-20,26-29H,4-11,14-18,37H2,1-3H3,(H2,38,47)(H,39,45)(H,40,46)(H,41,49)(H,42,50)(H,43,51)/t26-,27-,28-,29-/m0/s1
InChi Key
LHVYYJGFOAKRPP-DZUOILHNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-19876-10 |
---|---|
Supplier Part Number | 19876-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19876m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 223104-29-8 |