We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Ag-120; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
Cayman Ag-120; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$184.00
Your Price
$184.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-19894-10 |
MFG.PART: | 19894-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) that specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of 2-hydroxyglutarate.1 AG-120 may induce cellular differentiation as well as inhibit proliferation in IDH1-expressing tumor cells.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2S)-1-(4-cyano- 2-pyridinyl)- 5-oxo-L-prolyl- 2-(2-chloro phenyl)-N-(3,3- difluoro cyclobutyl)- N2-(5-fluoro- 3-pyridinyl)- glycinamide
CAS Number
1448347-49-6
Synonyms
- Ivosidenib
Molecular Formula
C28H22ClF3N6O3
Formula Weight
583.0
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
λmax
246, 307 nm
SMILES
O=C1CC[C@@H](C(N([C@H](C(NC2CC(F)(F)C2)=O)C3=C(Cl)C=CC=C3)C4=CC(F)=CN=C4)=O)N1C5=NC=CC(C#N)=C5
InChi Code
InChI=1S/C28H22ClF3N6O3/c29-21-4-2-1-3-20(21)25(26(40)36-18-11-28(31,32)12-18)37(19-10-17(30)14-34-15-19)27(41)22-5-6-24(39)38(22)23-9-16(13-33)7-8-35-23/h1-4,7-10,14-15,18,22,25H,5-6,11-12H2,(H,36,40)/t22-,25-/m0/s1
InChi Key
WIJZXSAJMHAVGX-DHLKQENFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-19894-10 |
---|---|
Supplier Part Number | 19894-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19894m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1448347-49-6 |