We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Acalabrutinib; Purity- Greater Than Or Equal To 95%; Size-
Cayman Acalabrutinib; Purity- Greater Than Or Equal To 95%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$267.00
Your Price
$267.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-19899-25 |
| MFG.PART: | 19899-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Acalabrutinib is an irreversible inhibitor of Bruton’s tyrosine kinase (BTK). It can dose-dependently inhibit B cell receptor signaling in primary chronic lymphocytic leukemia cells.1 In kinase-inhibition assays, acalabrutinib was more selective than ibrutinib (Item No. 16274) for inhibiting BTK and did not inhibit EGFR, Itk, or Txk signaling.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-
CAS Number
1420477-60-6
Synonyms
- ACP-196
Molecular Formula
C26H23N7O2
Formula Weight
465.5
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 25 mg/ml
- DMSO: 25 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- Ethanol: 15 mg/ml
λmax
229, 283, 336 nm
SMILES
O=C(NC1=CC=CC=N1)C(C=C2)=CC=C2C3=C(C(N)=NC=C4)N4C([C@@H]5CCCN5C(C#CC)=O)=N3
InChi Code
InChI=1S/C26H23N7O2/c1-2-6-21(34)32-15-5-7-19(32)25-31-22(23-24(27)29-14-16-33(23)25)17-9-11-18(12-10-17)26(35)30-20-8-3-4-13-28-20/h3-4,8-14,16,19H,5,7,15H2,1H3,(H2,27,29)(H,28,30,35)/t19-/m0/s1
InChi Key
WDENQIQQYWYTPO-IBGZPJMESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19899-25 |
|---|---|
| Supplier Part Number | 19899-25 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/19899m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1420477-60-6 |