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Cayman Nsc 59984; Purity- Greater Than Or Equal To 98%; Size- 1 M
Cayman Nsc 59984; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$32.00
Your Price
$32.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-19919-1 |
MFG.PART: | 19919-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
NSC 59984 is a reactivator of p53 that restores wild-type p53 signaling by activating p73-dependent apoptosis in mutant p53-expressing colon cancer cells. It is reported to induce cell death in colon cancer cells (EC50 = 8.38 µM in p53-null HCT116 cells) without evident toxicity toward normal cells. NSC 59984 has been shown to induce p53 mutant protein degradation via MDM2-mediated ubiquitination.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-(4-methyl- 1-piperazinyl)- 3-(5-nitro- 2-furanyl)- 2-propen- 1- one
CAS Number
803647-40-7
Molecular Formula
C12H15N3O4
Formula Weight
265.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 5 mg/ml
λmax
237, 276, 350 nm
SMILES
CN1CCN(C(/C=C/C2=CC=C([N+]([O-])=O)O2)=O)CC1
InChi Code
InChI=1S/C12H15N3O4/c1-13-6-8-14(9-7-13)11(16)4-2-10-3-5-12(19-10)15(17)18/h2-5H,6-9H2,1H3/b4-2+
InChi Key
QKTRIGNWBRHBFV-DUXPYHPUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-19919-1 |
---|---|
Supplier Part Number | 19919-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19919m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 803647-40-7 |