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Cayman At-406; Purity- Greater Than Or Equal To 95%; Size- 5 Mg;
Cayman At-406; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$199.00
Your Price
$199.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-19929-5 |
MFG.PART: | 19929-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
AT-406 is an orally bioavailable Smac/DIABLO mimetic and antagonist of the inhibitor of apoptosis proteins (IAPs). It binds to XIAP, cIAP1, and cIAP2 proteins with Ki values of 66.4, 1.9, and 5.1 nM, respectively.1 It has been shown to inhibit cancer cell growth in various human cancer cell lines and to induce apoptosis in xenograft tumors in mice.1,2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(5S,8S,10aR)- N-(diphenyl methyl)deca hydro-5-[[(2S) -2-(methylamino) -1-oxopropyl] amino]-3-(3- methyl-1-oxo butyl)-6-oxo- pyrrolo[1,2-a] [1,5]diazocine -8-carboxamide
CAS Number
1071992-99-8
Synonyms
- SM-406
Molecular Formula
C32H43N5O4
Formula Weight
561.7
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 12 mg/ml
- DMSO: 25 mg/ml
- DMSO:PBS(pH 7.2) (1:2): 0.33 mg/ml
- Ethanol: 20 mg/ml
SMILES
O=C(NC(C1=CC=CC=C1)C2=CC=CC=C2)[C@H]3N4C([C@@H](NC([C@@H](NC)C)=O)CN(C(CC(C)C)=O)CC[C@@]4([H])CC3)=O
InChi Code
InChI=1S/C32H43N5O4/c1-21(2)19-28(38)36-18-17-25-15-16-27(37(25)32(41)26(20-36)34-30(39)22(3)33-4)31(40)35-29(23-11-7-5-8-12-23)24-13-9-6-10-14-24/h5-14,21-22,25-27,29,33H,15-20H2,1-4H3,(H,34,39)(H,35,40)/t22-,25+,26-,27-/m0/s1
InChi Key
LSXUTRRVVSPWDZ-MKKUMYSQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-19929-5 |
---|---|
Supplier Part Number | 19929-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19929m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 1071992-99-8 |