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Cayman Gsk481; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
Cayman Gsk481; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$243.00
Your Price
$243.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-20308-10 |
MFG.PART: | 20308-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
DG-172 is an orally available inverse agonist of PPARβ/δ (IC50 = 27 nM), down-regulating transcription of ANGPTL4 in mouse myoblasts (IC50 = 9.5 nM). It alters the differentiation of bone marrow cells, augmenting GM-CSF-induced development into subsets of mature and immature dendritic cells. Inverse agonists of PPARβ/δ, including DG-172, inhibit cancer cell invasion through suppression of ANGPTL4 expression.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2- bromo-αZ- [[4-(4- methyl-1- piperazinyl)phenyl]methylene]- benzeneacetonitrile, dihydrochloride
CAS Number
1361504-77-9
Molecular Formula
C20H20BrN3 • 2HCl
Formula Weight
455.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 20 mg/ml
λmax
241, 348 nm
SMILES
CN1CCN(C2=CC=C(/C=C(C#N)/C3=C(Br)C=CC=C3)C=C2)CC1.Cl.Cl
InChi Code
InChI=1S/C20H20BrN3.2ClH/c1-23-10-12-24(13-11-23)18-8-6-16(7-9-18)14-17(15-22)19-4-2-3-5-20(19)21;;/h2-9,14H,10-13H2,1H3;2*1H/b17-14+;;
InChi Key
SABUORLIDVBCPI-WTLOABTRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-20308-10 |
---|---|
Supplier Part Number | 20308-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/20308m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1622849-58-4 |