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Cayman Lagosin; Purity- Greater Than Or Equal To 95%; Size- 5 Mg
Cayman Lagosin; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$1,290.45
Your Price
$1,290.45
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-20600-5 |
| MFG.PART: | 20600-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
NSC 405020 binds to the hemopexin (PEX) domain of the membrane type-1 matrix metalloproteinase (MT1-MMP/MMP-14). It disrupts MT1-MMP homodimerization without affecting its catalytic activity in an assay using the MT1-MMP CAT domain, which is involved in its tumor promoting function (IC50 > 100 µM). In a mouse tumor xenograft model, it reduces tumor growth through a cell death-independent mechanism when injected intratumorally at a dose of 0.5 mg/kg three times per week for two weeks. NSC 405020 (1 µM) applied to HSC5 cells prevents arsenic-mediated invasion while also decreasing the expression of MT1-MMP and pERK.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,4-dichloro-
CAS Number
7497-07-6
Molecular Formula
C12H15Cl2NO
Formula Weight
260.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
238 nm
SMILES
ClC1=CC(C(N([H])C(C)CCC)=O)=CC=C1Cl
InChi Code
InChI=1S/C12H15Cl2NO/c1-3-4-8(2)15-12(16)9-5-6-10(13)11(14)7-9/h5-8H,3-4H2,1-2H3,(H,15,16)
InChi Key
ARDYECYBETXQFD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20600-5 |
|---|---|
| Supplier Part Number | 20600-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/20600m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | AU |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 6834-98-6 |