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Cayman Tx-1918; Purity- Greater Than Or Equal To 98%; Size- 1 Mg
Cayman Tx-1918; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$32.00
Your Price
$32.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-20840-1 |
MFG.PART: | 20840-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
TX-1918 is a cell-permeable tyrphostin derivative that inhibits eukaryotic elongation factor-2 kinase (eEF-2K; IC50 = 440 nM). It inhibits Src, PKA, PKC, and EGFR kinases at much higher concentrations (IC50s = 4.4, 44, 44, and 440 µM, respectively). TX-1918 disrupts the proliferation of HepG2 and HCT116 tumor cells (EC50s = 2.07 and 230 µM, respectively) with ≥5,000-fold and ≥90-fold reduced mitochondrial- and hepato-toxicity, respectively when compared with the tyrphostin AG-17 (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[(4-hydroxy -3,5-dimethyl phenyl)methyl ene]-4-cyclo pentene-1,3- dione
CAS Number
503473-32-3
Molecular Formula
C14H12O3
Formula Weight
228.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: slightly
- DMSO: 0.33 mg/ml
- Ethanol: slightly
λmax
220, 248, 370 nm
SMILES
CC1=C(O)C(C)=CC(/C=C2C(C=CC\2=O)=O)=C1
InChi Code
InChI=1S/C14H12O3/c1-8-5-10(6-9(2)14(8)17)7-11-12(15)3-4-13(11)16/h3-7,17H,1-2H3
InChi Key
YHWRISYBKMXSGJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-20840-1 |
---|---|
Supplier Part Number | 20840-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/20840m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 503473-32-3 |