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Cayman (E)-5-(2-Bromovinyl)Uracil; Purity- Greater Than Or Equal
Cayman (E)-5-(2-Bromovinyl)Uracil; Purity- Greater Than Or Equal To 95%; Size- 250 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$299.00
Your Price
$299.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-21030-250 |
| MFG.PART: | 21030-250 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo.1,2,3 BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner.1,4 It enhances the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil (5-FU; Item No. 14416) in a P388 murine leukemia model when administered at a dose of 200 µmol/kg, increasing survival time.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[(1E)-2-
CAS Number
69304-49-0
Synonyms
- BVU
Molecular Formula
C6H5BrN2O2
Formula Weight
217.0
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 60 mg/mL
- DMSO: 53 mg/mL
- Ethanol: 0.8 mg/mL
- PBS (pH 7.2): 8 mg/mL
λmax
250, 290 nm
SMILES
O=C1NC(NC=C1/C=C/Br)=O
InChi Code
InChI=1S/C6H5BrN2O2/c7-2-1-4-3-8-6(11)9-5(4)10/h1-3H,(H2,8,9,10,11)/b2-1+
InChi Key
BLXGZIDBSXVMLU-OWOJBTEDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21030-250 |
|---|---|
| Supplier Part Number | 21030-250 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/21030m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CA |
| ProductLine | CAYM |
| Qty | 250 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 69304-49-0 |