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Cayman Dpre1-In2; Size- 25 Mg
Cayman Dpre1-In2; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$618.00
Your Price
$618.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-21034-25 |
| MFG.PART: | 21034-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
DprE1-IN-2 is an antitubercular agent that is active against M. tuberculosis in vitro, with MIC values ranging from 0.5 to 1.56 μM.1 It is an inhibitor of decaprenylphosphoryl-β-D-ribose 2-epimerase (DprE1; IC50 = 32 nM), an enzyme involved in mycobacterial cell wall biogenesis. DrpE1-IN-2 (300 mg/kg) reduces lung bacterial burden in a mouse model of chronic tuberculosis infection and exhibits a synergistic effect when administered in combination with TMC207 (Item No. 20247).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[[6-(di
CAS Number
1615713-87-5
Molecular Formula
C19H24N6O2
Formula Weight
368.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 2mg/mL
- DMSO: 2mg/mL
- DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL
λmax
214, 253, 294 nm
SMILES
CC1=CN=C2C(N(CC3=C(C)C(N(C)C)=NC=N3)C=C2C(NCCO)=O)=C1
InChi Code
InChI=1S/C19H24N6O2/c1-12-7-16-17(21-8-12)14(19(27)20-5-6-26)9-25(16)10-15-13(2)18(24(3)4)23-11-22-15/h7-9,11,26H,5-6,10H2,1-4H3,(H,20,27)
InChi Key
BLNAAWXUNQHVNT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21034-25 |
|---|---|
| Supplier Part Number | 21034-25 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/21034m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1615713-87-5 |