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Cayman Ly2606368; Purity- Greater Than Or Equal To 98%; Size- 5 M
Cayman Ly2606368; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$486.00
Your Price
$486.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-21490-5 |
MFG.PART: | 21490-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas., Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling., ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM). It can also inhibit the serine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
[4-(1,1-dimethylethyl) -1-piperidinyl] [4-(hydroxydiphenylmethyl) -2H-1,2,3-triazol -2-yl]-methanone
CAS Number
2205032-89-7
Molecular Formula
C25H30N4O2
Formula Weight
418.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 10 mg/ml
λmax
240 nm
SMILES
CC(C)(C)C1CCN(C(N2N=C(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)C=N2)=O)CC1
InChi Code
InChI=1S/C25H30N4O2/c1-24(2,3)19-14-16-28(17-15-19)23(30)29-26-18-22(27-29)25(31,20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,18-19,31H,14-17H2,1-3H3
InChi Key
LPTMHNPBMQCQPG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
SKU | CAYM-21490-5 |
---|---|
Supplier Part Number | 21490-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/21490m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1234015-52-1 |