We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Rsm-932a; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
Cayman Rsm-932a; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$107.00
Your Price
$107.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-21518-5 |
MFG.PART: | 21518-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
RSM-932A is a selective inhibitor of choline kinase α (CHOKα; IC50s = 1 and >50 μM for CHOKα and β, respectively).1 It induces apoptosis via CHOP signaling and endoplasmic reticulum (ER) stress in MDA-MB-231, MCF-7, SW620, and H460 cancer cells, but it only induces cell cycle arrest and not apoptosis in NCM460 and MCF-10A normal epithelial cells.2 RSM-932A inhibits the growth of HT-29 colon cancer cells in vitro (IC50 = 1.15 μM) and in vivo in a mouse xenograft model (ED50 = 7.5 mg/kg).1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,1-[[[1,1- biphenyl]-4,4- diyl]bis(methylene)] bis[4-[(4-chloro phenyl)methyl amino]-quinolinium, di bromide
CAS Number
850807-63-5
Molecular Formula
C46H38Cl2N4 • 2Br
Formula Weight
877.5
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 3 mg/ml
- DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml
λmax
233, 255, 364 nm
SMILES
ClC1=CC=C(N(C2=CC=[N+](CC3=CC=C(C4=CC=C(C[N+]5=C(C=CC=C6)C6=C(N(C7=CC=C(Cl)C=C7)C)C=C5)C=C4)C=C3)C8=C2C=CC=C8)C)C=C1.[Br-].[Br-]
InChi Code
InChI=1S/C46H38Cl2N4.2BrH/c1-49(39-23-19-37(47)20-24-39)43-27-29-51(45-9-5-3-7-41(43)45)31-33-11-15-35(16-12-33)36-17-13-34(14-18-36)32-52-30-28-44(42-8-4-6-10-46(42)52)50(2)40-25-21-38(48)22-26-40;;/h3-30H,31-32H2,1-2H3;2*1H/q+2;;/p-2
InChi Key
DGBVSSXGHKAASQ-UHFFFAOYSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-21518-5 |
---|---|
Supplier Part Number | 21518-5 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/21518m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 850807-63-5 |