We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman G244-Lm; Size- 25 Mg
Cayman G244-Lm; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$416.00
Your Price
$416.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-21876-25 |
| MFG.PART: | 21876-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
G244-LM is an inhibitor of Wnt signaling.1 It inhibits Wnt3a-induced signaling in HEK293 human and 10T1/2 mouse cells in a reporter assay. It also inhibits Wnt signaling and colony formation in COLO-320DM and SW403, but not HCT-15 or DLD-1, colorectal cancer cells when used at a concentration of 0.2 µM for seven to 13 days. G244-LM inhibits growth of mouse intestinal organoids (IC50 = 0.11 µM) and organoid spheroids cultured from small intestine adenomas isolated from ApcMin mice, which exhibit constitutively activated Wnt/β-catenin signaling.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,5,7,8-tetra
CAS Number
1563007-08-8
Molecular Formula
C18H22N4O3S2
Formula Weight
406.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 2 mg/ml
- DMSO: 5 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- Ethanol: 0.25 mg/ml
λmax
213, 235, 300 nm
SMILES
O=C(N=C(N1CCN(C2=C(S(C)(=O)=O)C=CC=C2)CC1)N3)C4=C3CCSC4
InChi Code
InChI=1S/C18H22N4O3S2/c1-27(24,25)16-5-3-2-4-15(16)21-7-9-22(10-8-21)18-19-14-6-11-26-12-13(14)17(23)20-18/h2-5H,6-12H2,1H3,(H,19,20,23)
InChi Key
JSQPAEVPPSCQMV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21876-25 |
|---|---|
| Supplier Part Number | 21876-25 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/21876m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1563007-08-8 |