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Cayman Ono-7300243; Purity- Greater Than Or Equal To 98%; Size- 1
Cayman Ono-7300243; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$40.00
Your Price
$40.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-22052-1 |
MFG.PART: | 22052-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
VEGFR tyrosine kinase inhibitor II is a pyridinyl-anthranilamide compound that inhibits the kinase activities of VEGFR2 (KDR), VEGFR1 (FLT1), and c-Kit (IC50s = 20, 180, and 240 nM, respectively). It displays minimal activity against c-Src and EGFR (IC50s = 7 and 7.3 µM, respectively) and is inactive against Cdk1, c-Met, IGF-1R, and PKA (IC50s > 10 µM). VEGFR tyrosine kinase inhibitor II has been investigated for its potential to inhibit tumor induced angiogenesis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(4-chlorophenyl)-2-[(4-pyridinylmethyl)amino]-benzamide
CAS Number
269390-69-4
Synonyms
- Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitor II
Molecular Formula
C19H16ClN3O
Formula Weight
337.8
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 50 mg/ml
- DMSO: 50 mg/ml
- DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
- Ethanol: 25 mg/ml
λmax
220, 260, 345 nm
SMILES
ClC1=CC=C(NC(C2=CC=CC=C2NCC3=CC=NC=C3)=O)C=C1
InChi Code
InChI=1S/C19H16ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h1-12,22H,13H2,(H,23,24)
InChi Key
GGPZCOONYBPZEW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-22052-1 |
---|---|
Supplier Part Number | 22052-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/22052m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 638132-34-0 |