We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Cgs 15943; Purity- Greater Than Or Equal To 95%; Size- 10
NETA PART: | CAYM-22073-10 |
MFG.PART: | 22073-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
CGS 15943 is an orally bioavailable non-xanthine antagonist at adenosine (A) receptors with IC50 values of 3.5, 4.2, 16, and 51 nM in CHO cells transfected with human recombinant A1, A2A, A2B, and A3 receptors, respectively., It also binds to the phosphatidylinositol 3-kinase (PI3K) catalytic subunit p110γ, and it inhibits proliferation of HCC hepatocellular carcinoma and PDAC pancreatic cancer adenocarcinoma cells through the PI3K/Akt signaling pathway. In rats, CGS 15943 (0.1-10 mg/kg, i.p.) increases locomotor activity in a dose-dependent manner. It also reinforces and reinstates cocaine-seeking in baboons through an adenosine-dependent mechanism.
WARNING This product is not for human or veterinary use.
Technical Information
- CGS 15943A
- DMF: 1 mg/ml
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml
- DMSO: 0.5 mg/ml
Shipping & Storage Information
SKU | CAYM-22073-10 |
---|---|
Supplier Part Number | 22073-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/22073m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 104615-18-1 |