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Cayman Ipsapirone; Purity- Greater Than Or Equal To 98%; Size- 25
NETA PART: | CAYM-22075-25 |
MFG.PART: | 22075-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Ipsapirone is a partial agonist of the serotonin (5-HT) receptor 5-HT1A (Ki = 10 nM in hippocampal membranes).1 It reduces 5-HT release in rat ventral hippocampus in vivo.2 Low doses of ipsapirone decrease, while high doses increase, extracellular dopamine release in murine nucleus accumbens.3 Extracellular dopamine levels in murine striatum increase following administration of ipsapirone at concentrations >0.1 mg/kg. Ipsapirone has anxiolytic effects in vivo, inhibiting foot shock-induced aggression and passive avoidance behavior in rats (ED50s = 2.2 and 0.5 mg/kg, respectively).4 Formulations containing ipsapirone have been used to treat depression and borderline personality disorder.5
WARNING This product is not for human or veterinary use.
Technical Information
- TVXQ 7821
- DMF: 10 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS (pH 7.2) (1:40): 0.025 mg/ml
- Ethanol: slightly soluble
Shipping & Storage Information
SKU | CAYM-22075-25 |
---|---|
Supplier Part Number | 22075-25 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/22075m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 25 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 95847-70-4 |