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Cayman D-Cycloserine; Purity- Greater Than Or Equal To 95%; Size-
NETA PART: | CAYM-22194-1 |
MFG.PART: | 22194-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
D-Cycloserine is an NMDA receptor (NMDAR) partial agonist with antibiotic activity. It selectively binds to the glycine binding site (Ki = 2.33 μM) over the glutamate binding site (Ki = >100 μM). D-Cycloserine modulates memory in a T-maze footshock test in CD-1 mice with optimal memory retention at doses of 10-30 mg/kg. Administration of D-cycloserine (20-40 mg/kg) improves memory retention in ‘senescence-accelerated’ mice which exhibit impaired learning and memory. D-Cycloserine inhibits L-alanine racemase and D-alanine:D-alanine ligase, enzymes essential to peptidoglycan synthesis and bacterial cell wall formation. Formulations containing D-cycloserine have been used as second-line agents to treat drug resistant tuberculosis.
WARNING This product is not for human or veterinary use.
Technical Information
- (+)-Cycloserine
- α-Cycloserine
- (R)-Cycloserine
- NSC 76029
- NSC 154851
- DMSO: 1 mg/ml
- PBS (pH 7.2): 10 mg/ml
Shipping & Storage Information
SKU | CAYM-22194-1 |
---|---|
Supplier Part Number | 22194-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/22194m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 68-41-7 |