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Cayman Cay10722; Purity- Greater Than Or Equal To 98%; Size- 25 M
Cayman Cay10722; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$533.00
Your Price
$533.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-22404-25 |
MFG.PART: | 22404-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
NVS-CECR2-1 is a potent inhibitor of CECR2 (cat eye syndrome chromosome region, candidate 2), a component of chromatin complexes that regulate gene expression controlling development. It binds CECR2 with high affinity (IC50 = 0.047 µM by Alpha screen, Kd = 0.80 µM by ITC). NVS-CECR2-1 demonstrates no crossreactivity in a panel of 48 bromodomains and has no major activity in kinase, protease, and receptor panels. It shows robust activity in cells by FRAP assay, due to its slow off-rate, and has no acute toxicity. See the website for more information.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-cyclopropyl- 2-(propyl sulfonyl)- 6-[1-(2,2,6,6- tetramethyl- 4-piperidinyl)- 1H-indol- 5-yl]- 4-pyrimidin amine
CAS Number
1992047-61-6
Synonyms
- NVS-1
Molecular Formula
C27H37N5O2S
Formula Weight
495.7
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMSO: 0.3 mg/ml
λmax
267 nm
SMILES
O=S(C1=NC(NC2CC2)=CC(C3=CC(C=CN4C5CC(C)(C)NC(C)(C)C5)=C4C=C3)=N1)(CCC)=O
InChi Code
InChI=1S/C27H37N5O2S/c1-6-13-35(33,34)25-29-22(15-24(30-25)28-20-8-9-20)18-7-10-23-19(14-18)11-12-32(23)21-16-26(2,3)31-27(4,5)17-21/h7,10-12,14-15,20-21,31H,6,8-9,13,16-17H2,1-5H3,(H,28,29,30)
InChi Key
XVECNLUKQDKOST-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-22404-25 |
---|---|
Supplier Part Number | 22404-25 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/22404m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 25 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 388086-13-3 |