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Cayman Mertansine; Purity- Greater Than Or Equal To 98%; Size- 5
Cayman Mertansine; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$93.00
Your Price
$93.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-22483-5 |
MFG.PART: | 22483-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Mertansine is a thiol-containing derivative of maytansine that is cytotoxic to human epidermoid carcinoma KB and human breast cancer SK-BR-3 cells (IC50 = 1.10 nM for both).1 Formulations containing mertansine have been studied for the treatment of multiple myeloma and squamous cell carcinoma.2,3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N2′-deacetyl- N2′-(3- mercapto-1- oxopropyl)- maytansine
CAS Number
139504-50-0
Synonyms
- DM1 Compound
Molecular Formula
C35H48ClN3O10S
Formula Weight
738.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 33 mg/ml
- DMF:PBS (pH7.2) (1:30): 0.03 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 0.25 mg/ml
λmax
233, 253 nm
SMILES
C[C@@]1([C@@H](O1)[C@H](C)[C@]([H])(C[C@](N2)(O)[C@]([H])(OC)/C=C/C=C(CC3=CC(OC)=C(Cl)C4=C3)\C)OC2=O)[C@@]([H])(OC([C@@H](N(C)C(CCS)=O)C)=O)CC(N4C)=O
InChi Code
InChI=1S/C35H48ClN3O10S/c1-19-10-9-11-26(46-8)35(44)18-25(47-33(43)37-35)20(2)31-34(4,49-31)27(48-32(42)21(3)38(5)28(40)12-13-50)17-29(41)39(6)23-15-22(14-19)16-24(45-7)30(23)36/h9-11,15-16,20-21,25-27,31,44,50H,12-14,17-18H2,1-8H3,(H,37,43)/b11-9+,19-10+/t20-,21+,25+,26-,27+,31+,34+,35+/m1/s1
InChi Key
ANZJBCHSOXCCRQ-FKUXLPTCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-22483-5 |
---|---|
Supplier Part Number | 22483-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/22483m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 139504-50-0 |