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Cayman 2-Deoxycytidine 5-Diphosphate (Sodium Salt Hydrate); Pur
Cayman 2-Deoxycytidine 5-Diphosphate (Sodium Salt Hydrate); Purity- Greater Than Or Equal To 95%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$140.00
Your Price
$140.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-22982-25 |
MFG.PART: | 22982-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A (Item No. ) that has anticancer activity. It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 µM) but not to carboplatin-resistant A2780 (A2780/CP70) cells (IC50 = >100 µM). It is selective for A2780 cells over non-cancerous ARPE19 cells (IC50 = 1,660 µM). 4-oxo-27-TBDMS Withaferin A induces DNA fragmentation in A2780 cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(5β,6β,22R)- 27-[[(1,1- dimethyl ethyl)dimethyl silyl]oxy]- 5,6-epoxy-22- hydroxy-1,4- dioxo-ergosta- 2,24-dien-26- oic acid, δ-lactone
CAS Number
1214886-31-3
Molecular Formula
C34H50O6Si
Formula Weight
582.9
Purity
≥98%
Formulation
A solution in ethanol
Solubility
- DMF: 5mg/mL
- DMSO: 5mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL
λmax
224 nm
SMILES
O=C(C=C1)[C@@]2(C)[C@@]([C@H]3C[C@]4([H])[C@]2([H])CC[C@@]5(C)[C@@]4([H])CC[C@]5([H])[C@H](C)[C@@]6([H])CC(C)=C(CO[Si](C)(C)C(C)(C)C)C(O6)=O)(O3)C1=O
InChi Code
InChI=1S/C34H50O6Si/c1-19-16-26(39-30(37)22(19)18-38-41(8,9)31(3,4)5)20(2)23-10-11-24-21-17-29-34(40-29)28(36)13-12-27(35)33(34,7)25(21)14-15-32(23,24)6/h12-13,20-21,23-26,29H,10-11,14-18H2,1-9H3/t20-,21-,23+,24-,25-,26+,29+,32+,33-,34+/m0/s1
InChi Key
RZWFBNOFUAHADD-VTYRCZOESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
SKU | CAYM-22982-25 |
---|---|
Supplier Part Number | 22982-25 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/22982m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 25 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 151151-32-5 |