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Cayman Cathepsin L Inhibitor; Purity- Greater Than Or Equal To 95
Cayman Cathepsin L Inhibitor; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$107.00
Your Price
$107.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-23249-5 |
MFG.PART: | 23249-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Asarinin is a lignan that has been found in A. sieboldii. It is an epimer of sesamin (Item No. ) and a noncompetitive inhibitor of Δ5-desaturase (Ki = 0.28 mM). It is selective for Δ5-desaturase over Δ6- and Δ9-desaturase. Asarinin is cytotoxic to A2780 and SKOV3 ovarian cancer cells (IC50s = 38.45 and 60.87 µM, respectively) but not immortalized ovarian surface epithelial cells (IC50 = >200 µM). It induces apoptosis and activates caspase-3, -8, and -9 in A2780 and SKOV3 cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5,5-[(1R,3aS, 4S,6aS)-tetra hydro-1H,3H- furo[3,4-c] furan-1,4-diyl] bis-1,3- benzodioxole
CAS Number
133-04-0
Synonyms
- (–)-Asarinin
- L-Asarinin
- Desgeranyloxyarmatumin
- (–)-Episesamin
Molecular Formula
C20H18O6
Formula Weight
354.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20mg/mL
- DMSO: 10mg/mL
- DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL
λmax
237, 288 nm
SMILES
[H][C@]1([C@@H](C2=CC(OCO3)=C3C=C2)OC4)[C@]4([H])[C@H](C5=CC(OCO6)=C6C=C5)OC1
InChi Code
InChI=1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19-,20+/m1/s1
InChi Key
PEYUIKBAABKQKQ-FQZPYLGXSA-N
Origin
Plant/Magnoliae flos
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-23249-5 |
---|---|
Supplier Part Number | 23249-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/23249m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 167498-29-5 |