Cayman Msx-122; Purity- Greater Than Or Equal To 98%; Size- 5 Mg

MSX-122 is a small molecule partial antagonist of C-X-C chemokine 4 (CXCR4; IC₅₀ = ~10 nM).¹ It reduces inflammation and infiltration of CXCR4⁺ cells in a dextran sulfate (Item No. 23250) model of experimental colitis in mice. Specifically, it prevents the production of TNF-α, IL-1β, and IL-6. MSX-122 also reduces TNF-α secretion by macrophages infected with patient-derived invasive E. coli. It decreases metastases in mouse models utilizing MDA-MB-231 breast cancer or 686LN-Ms squamous cell carcinoma cells injected intravenously or OMM2.3 melanoma cells inoculated into the eye.

WARNING This product is not for human or veterinary use.