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Cayman Nsc 319726; Purity- Greater Than Or Equal To 95%; Size- 5
Cayman Nsc 319726; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$97.00
Your Price
$97.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-23701-5 |
MFG.PART: | 23701-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
3-Iodotyrosine is an inhibitor of tyrosine hydroxylase (Ki = 0.39 µM) and an intermediate in the synthesis of thyroid hormones., It has been incorporated into proteins as a non-natural amino acid for use as a label to detect protein-protein interactions. 3-Iodotyrosine induces the formation of α-synuclein aggregates and tyrosine hydroxylase-positive inclusions in primary substantia nigra neurons when used at concentrations of 5 and 10 nM. It induces parkinsonism in mice, reducing locomotor activity and inducing bradykinesia in the open field test when administered at an intrastriatal dose of 10 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-iodo-L- tyrosine
CAS Number
70-78-0
Synonyms
- 3-iodo-4-Hydroxyphenylalanine
- Monoiodotyrosine
- NSC 210787
Molecular Formula
C9H10INO3
Formula Weight
307.1
Purity
≥95%
Formulation
A crystalline solid
Solubility
- PBS (pH 7.2): 0.15 mg/mL
λmax
283 nm
SMILES
IC1=C(O)C=CC(C[C@H](N)C(O)=O)=C1
InChi Code
InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1
InChi Key
UQTZMGFTRHFAAM-ZETCQYMHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-23701-5 |
---|---|
Supplier Part Number | 23701-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/23701m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 71555-25-4 |