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Cayman 1-(2,5-Dimethoxybenzyl)Piperazine (Hydrochloride); Purity-
Cayman 1-(2,5-Dimethoxybenzyl)Piperazine (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$109.00
Your Price
$109.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-24017-5 |
| MFG.PART: | 24017-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Flutamide is an androgen receptor antagonist (Kis = 1.3 and 7.5 µM for the cytosolic rat ventral prostate and anterior pituitary receptors, respectively) and a prodrug form of 2-hydroxy flutamide (Item No. ). Flutamide is converted to 2-hydroxy flutamide by the cytochrome P450 (CYP) isoform CYP1A2 in human liver microsomes. It is cytotoxic to PC3 and LNCaP prostate cancer cells with IC50 values of 98.8 and 81.8 µM, respectively. Flutamide (50 mg/kg per day) reduces tumor growth in a PC-82 mouse xenograft model. Formulations containing flutamide have been used in the treatment of prostate cancer.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-methyl-N-[4
CAS Number
13311-84-7
Synonyms
- Niftolide
- NSC 147834
- NSC 251876
- SCH 13521
Molecular Formula
C11H11F3N2O3
Formula Weight
276.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
λmax
226, 294 nm
SMILES
O=C(C(C)C)NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1
InChi Code
InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)
InChi Key
MKXKFYHWDHIYRV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24017-5 |
|---|---|
| Supplier Part Number | 24017-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/24017m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 374897-99-1 |