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Cayman Sugammadex (Sodium Salt); Purity- Greater Than Or Equal To
NETA PART: | CAYM-24096-1 |
MFG.PART: | 24096-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Gefitinib-d6 is intended for use as an internal standard for the quantification of gefitinib (Item No. ) by GC- or LC-MS. Gefitinib is an EGFR inhibitor (IC50s = 0.023-0.079 µM). It inhibits colony formation of GEO colon, ZR-75-1 and MCF-10A breast, and OVCAR-3 ovarian cancer cell lines in soft agar assays (IC50s = 0.2-0.4 µM). Gefitinib (0.1 to 1 µM) induces apoptosis and inhibits EGFR autophosphorylation in the same cells. In vivo, gefitinib (1.25, 2.5, and 5 mg/kg) reduces tumor volume and increases survival in a GEO mouse xenograft model. Formulations containing gefitinib have been used in the treatment of non-small cell lung cancer (NSCLC).
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- Ethanol: 0.3 mg/ml
Shipping & Storage Information
SKU | CAYM-24096-1 |
---|---|
Supplier Part Number | 24096-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/24096m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 343306-79-6 |