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Cayman Flumethasone; Purity- Greater Than Or Equal To 98%; Size-
Cayman Flumethasone; Purity- Greater Than Or Equal To 98%; Size- 100 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$66.00
Your Price
$66.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-24184-100 |
| MFG.PART: | 24184-100 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Flumethasone is an agonist of glucocorticoid and mineralocorticoid receptors with EC50 values of 0.26 and 0.494 nM, respectively, in CV-1 cells expressing human receptors.1 In vitro, it inhibits the growth of UM-UC-3, TCC-SUP, and 5637 urothelial carcinoma cell lines at a concentration of 100 nM.2 Flumethasone (5 mg per animal) decreases tumor necrosis factor (TNF) production ex vivo in blood cells collected by bronchoalveolar lavage (BAL) from calves with experimentally-induced local lung inflammation.3 It also inhibits phytohemagglutinin-induced delayed hypersensitivity in calf skin. In vivo, flumethasone (5 μM) impairs cell cycle re-entry of cardiac cells seven days post cryo-injury to the heart and impairs cardiac regeneration in zebrafish.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6α,9-difluoro
CAS Number
2135-17-3
Synonyms
- NSC 5402
- NSC 54702
- U-10974
Molecular Formula
C22H28F2O5
Formula Weight
410.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 25 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml
- Ethanol: 3 mg/ml
λmax
239 nm
SMILES
O=C1C=C[C@@]2(C)C([C@@H](F)C[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@]4(O)C(CO)=O)=C1
InChi Code
InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1
InChi Key
WXURHACBFYSXBI-GQKYHHCASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24184-100 |
|---|---|
| Supplier Part Number | 24184-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/24184m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 100 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 2135-17-3 |