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Cayman Pht-427; Purity- Greater Than Or Equal To 98%; Size- 25 Mg
Cayman Pht-427; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$166.00
Your Price
$166.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-24188-25 |
| MFG.PART: | 24188-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Buflomedil is a non-selective antagonist of α-adrenergic receptors (α-ARs) and vasoactive compound.,,, It binds to rat α1A- and α1B-ARs (Kis = 4.06 and 6.84 µM, respectively) and human platelet α2-ARs (IC50 = 1 µM) in radioligand binding assays., Buflomedil (0.06-60 µM) inhibits contraction of isolated canine saphenous veins induced by phenylephrine, clonidine (Item No. ), sympathetic nerve stimulation, or norepinephrine. It inhibits ADP-, collagen-, or epinephrine-induced aggregation of isolated human platelets when used at a concentration of 100 µM. Buflomedil (10 mg/kg) reduces hippocampal neuronal cell death in a rat model of carotid clamping-induced ischemia-reperfusion injury.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(1-pyrro
CAS Number
35543-24-9
Synonyms
- LL-1656
Molecular Formula
C17H25NO4 • HCl
Formula Weight
343.9
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 3mg/mL
- DMSO: 2mg/mL
- Ethanol: 3mg/mL
- PBS (pH 7.2): 10mg/mL
SMILES
COC1=CC(OC)=C(C(CCCN2CCCC2)=O)C(OC)=C1.Cl
InChi Code
InChI=1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H
InChi Key
ZDPACSAHMZADFZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24188-25 |
|---|---|
| Supplier Part Number | 24188-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/24188m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1191951-57-1 |