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Cayman Ubp 302; Purity- Greater Than Or Equal To 98%; Size- 1 Mg
NETA PART: | CAYM-24309-1 |
MFG.PART: | 24309-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
UBP 302 is an antagonist of glutamate receptor 5 (GluR5) subunit-containing kainate receptors that inhibits kainate-induced responses in isolated rat dorsal roots (Kd = 402 nM). In vitro, UBP 302 inhibits gamma frequency oscillations in the rat basolateral amygdala at a concentration of 25 µM, and blocks kainate receptor signaling in layer III neurons within the mouse medial entorhinal cortex at 20 µM, abrogating the intense synaptic activity characteristic of the Up state of cortical slow oscillation., In vivo, UBP 302 (250 mg/kg) significantly reduces seizure severity in a rat model of soman-induced status epilepticus.
WARNING This product is not for human or veterinary use.
Technical Information
- DMSO: 50 mM
Shipping & Storage Information
SKU | CAYM-24309-1 |
---|---|
Supplier Part Number | 24309-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/24309m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 745055-91-8 |