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Cayman 3-Hydroxy Decanoic Acid, 3-Hydroxy-Decanoic Acid, 25 Mg
Cayman 3-Hydroxy Decanoic Acid, 3-Hydroxy-Decanoic Acid, 25 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$251.00
Your Price
$251.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-24613-25 |
MFG.PART: | 24613-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Ac-LEHD-AFC is a fluorogenic substrate that can be cleaved by caspase-4, -5, and -9. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-acetyl-L- leucyl-L-α- glutamyl-L- histidyl-N- [2-oxo-4- (trifluoro methyl)-2H-1- benzopyran-7- yl]-L-α- asparagine, trifluoro acetate salt
Synonyms
- N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin
- Caspase-9 substrate (Fluorogenic)
Molecular Formula
C33H38F3N7O11 • XCF3COOH
Formula Weight
765.7
Purity
≥95%
Emission
505 nm
Excitation
400 nm
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/ml
- DMSO: 2 mg/ml
- Ethanol: 2 mg/ml
- PBS (pH 7.2): 1 mg/ml
λmax
211, 340 nm
SMILES
O=C([C@H](CC1=CNC=N1)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC(C)=O)=O)=O)N[C@H](C(NC2=CC=C3C(C(F)(F)F)=CC(OC3=C2)=O)=O)CC(O)=O.FC(F)(C(O)=O)F
InChi Code
InChI=1S/C33H38F3N7O11.C2HF3O2/c1-15(2)8-22(39-16(3)44)31(52)41-21(6-7-26(45)46)29(50)42-23(9-18-13-37-14-38-18)32(53)43-24(12-27(47)48)30(51)40-17-4-5-19-20(33(34,35)36)11-28(49)54-25(19)10-17;3-2(4,5)1(6)7/h4-5,10-11,13-15,21-24H,6-9,12H2,1-3H3,(H,37,38)(H,39,44)(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,45,46)(H,47,48);(H,6,7)/t21-,22-,23-,24-;/m0./s1
InChi Key
IKHXNWAISFEPLL-JPIABUGISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-24613-25 |
---|---|
Supplier Part Number | 24613-25 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/24613m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 14292-26-3 |