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Cayman Dl-2,6-Dimethyl Heptanoic Acid, 2,6-Dimethyl-Heptanoic Aci
Cayman Dl-2,6-Dimethyl Heptanoic Acid, 2,6-Dimethyl-Heptanoic Acid, 50 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$209.00
Your Price
$209.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-24822-50 |
| MFG.PART: | 24822-50 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
PF-05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively). It inhibits formation of malonyl-CoA in primary rat hepatocytes (EC50 = 29.9 nM). In vivo, PF-05175157 inhibits formation of malonyl-CoA in the liver and skeletal muscle, inhibits hepatic de novo lipogenesis, and lowers the respiratory exchange rate in rats (ED50s = 6, 11, 7.8, and 3.5 mg/kg, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,4-dihydro-
CAS Number
1301214-47-0
Molecular Formula
C23H27N5O2
Formula Weight
405.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 25 mg/ml
λmax
212, 249 nm
SMILES
CC(N1[H])=NC2=C1C=C(C(N3CCC4(CC(C=NN5C(C)C)=C5C(C4)=O)CC3)=O)C=C2
InChi Code
InChI=1S/C23H27N5O2/c1-14(2)28-21-17(13-24-28)11-23(12-20(21)29)6-8-27(9-7-23)22(30)16-4-5-18-19(10-16)26-15(3)25-18/h4-5,10,13-14H,6-9,11-12H2,1-3H3,(H,25,26)
InChi Key
BDXXSFOJPYSYOC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24822-50 |
|---|---|
| Supplier Part Number | 24822-50 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/24822m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 2043506 |