Cayman Zingerone; Purity- Greater Than Or Equal To 98%; Size- 50

Zingerone is a phenolic ketone originally isolated from ginger that has antioxidant, anti-inflammatory, anticarcinogenic, and antidiarrheal activities.^1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay with an EC₅₀ value of 41.6 μmol.³ Zingerone (6 mg/kg per day) prevents myocardial expression of TNF-α, IL-1β, and IL-6 in rats following myocardial infarction induced by isoproterenol (Item No. 15592).⁴ It decreases 1,2-dimethylhydrazine-induced tumor incidence by 67% and aberrant crypt foci formation by 68.85% in rats when administered at a dose of 20 mg/kg per day.⁵ Zingerone (10 mM) decreases E. coli heat-labile enterotoxin-induced fluid accumulation in the ileal loop of mice.⁶

WARNING This product is not for human or veterinary use.