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Cayman Amtb; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
NETA PART: | CAYM-25336-5 |
MFG.PART: | 25336-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Deferiprone is an iron chelator that binds to iron in a 3:1 (ligand:iron) ratio and has antioxidant and neuroprotective activities. It reverses ferroptosis induced by erastin (Item No. ) in HT-1080 fibrosarcoma cells when used at a concentration of 100 µM as well as reduces levels of intracellular iron and inhibits lipid peroxidation in primary rat hepatocytes at 200 and 50 µM, respectively., Deferiprone reduces cholesterol diet-induced increases in the levels of amyloid-β (1-42) (Aβ42), Aβ40, and the phosphorylation of tau and glycogen synthase kinase-3β (GSK-3β) in the rabbit hippocampus when administered at a dose of 50 mg/kg. Formulations containing deferiprone have been used in the treatment of thalassemia.
WARNING This product is not for human or veterinary use.
Technical Information
- CGP 37391
- DN 18001AF
- MeOH:PBS (pH 7.2); (1:1): 0.5 mg/ml
- Methanol: 5 mg/ml
Shipping & Storage Information
SKU | CAYM-25336-5 |
---|---|
Supplier Part Number | 25336-5 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/25336m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 926023-82-7 |