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Cayman Glpg1690; Purity- Greater Than Or Equal To 98%; Size- 50 M
Cayman Glpg1690; Purity- Greater Than Or Equal To 98%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$593.00
Your Price
$593.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-25498-50 |
MFG.PART: | 25498-50 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
GLP1690 is a potent inhibitor of autotaxin (Ki = 15 nM).1 It inhibits the production of lysophosphatidic acid (LPA) in mouse, rat, and human plasma (IC50s = 418, 542, and 242 nM, respectively). GLPG1690 (30 mg/kg) reduces extracellular matrix deposition in the lung as well as LPA 18:2 levels in bronchoalveolar lavage fluid in a mouse model of pulmonary fibrosis induced by bleomycin (Item No. 13877).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[2-ethyl-6- [4-[2-(3- hydroxy-1- azetidinyl)-2- oxoethyl]-1- piperazinyl]- 8-methylimida zo[1,2-a] pyridin-3-yl] methylamino]- 4-(4-fluoro phenyl)-5- thiazolecarbo nitrile
CAS Number
1628260-79-6
Synonyms
- Ziritaxestat
Molecular Formula
C30H33FN8O2S
Formula Weight
588.7
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 80 mg/ml
λmax
252 nm
SMILES
O=C(N1CC(O)C1)CN2CCN(C3=CN4C(C(C)=C3)=NC(CC)=C4N(C5=NC(C6=CC=C(F)C=C6)=C(C#N)S5)C)CC2
InChi Code
InChI=1S/C30H33FN8O2S/c1-4-24-29(35(3)30-34-27(25(14-32)42-30)20-5-7-21(31)8-6-20)39-15-22(13-19(2)28(39)33-24)37-11-9-36(10-12-37)18-26(41)38-16-23(40)17-38/h5-8,13,15,23,40H,4,9-12,16-18H2,1-3H3
InChi Key
REQQVBGILUTQNN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-25498-50 |
---|---|
Supplier Part Number | 25498-50 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/25498m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 50 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1628260-79-6 |