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Cayman Methyl 2-(1h-Indazole-3-Carboxamido)-3-Methylbutanoate
Cayman Methyl 2-(1h-Indazole-3-Carboxamido)-3-Methylbutanoate - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$97.00
Your Price
$97.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-25580-1 |
| MFG.PART: | 25580-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
3-Hydroxyisobutyrate (3-HIB) is an intermediate in the metabolism of the branched-chain amino acid valine that is secreted by skeletal muscle., It dose-dependently increases fatty acid uptake by human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 0.1 to 100 mM. 3-HIB also increases fatty acid uptake and lipid accumulation in mouse skeletal muscle when administered in drinking water. The levels of 3-HIB in muscle are increased in db/db diabetic mice and in humans with diabetes. Human plasma levels are increased in obesity and correlate with a future risk of type 2 diabetes. In addition, human serum levels of 3-HIB decrease by 2.5-fold immediately following an exercise regimen of 2.5 hours of running for three days.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-hydroxy-2-
CAS Number
1219589-99-7
Synonyms
- 3-HIB
Molecular Formula
C4H7O3 • Na
Formula Weight
126.1
Purity
≥95%
Formulation
A crystalline solid
Solubility
- Ethanol: 5 mg/ml
- PBS (pH 7.2): 10 mg/ml
SMILES
OCC(C)C([O-])=O.[Na+]
InChi Code
InChI=1S/C4H8O3.Na/c1-3(2-5)4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
InChi Key
RBJZIQZDAZLXEK-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25580-1 |
|---|---|
| Supplier Part Number | 25580-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/25580m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1563540-10-2 |