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Cayman Sabinene; Purity- Greater Than Or Equal To 98%; Size- 25 M
![](https://netam2po.netascientific.info/media/skin/seal2.png)
![](https://netam2po.netascientific.info/media/skin/seal.png)
NETA PART: | CAYM-25777-25 |
MFG.PART: | 25777-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
(Ala1)-PAR4 (1-6) amide (mouse) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that induces aggregation of rat and human platelets in vitro (EC50s = 15 and 60 μM, respectively)., It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. (Ala1)-PAR4 (1-6) amide (mouse) induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips (EC50s = 11 and 110 μM, respectively) as well as inhibits calcium mobilization evoked by capsaicin (Item No. ) in rat sensory neurons., In vivo, (Ala1)-PAR4 (1-6) amide (mouse) (1-100 µg) increases latency to paw withdrawal and the nociceptive threshold in response to thermal and mechanical stimuli. (Ala1)-PAR4 (1-6) amide (mouse) (200 µg) also increases paw thickness in a rat paw edema assay.
WARNING This product is not for human or veterinary use.
Technical Information
- AY-NH2
- AYPGKF-NH2
- H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2
- PAR4-AP
- Proteinase-Activated Receptor 4 Activating Peptide
- Water: 1 mg/ml
Shipping & Storage Information
SKU | CAYM-25777-25 |
---|---|
Supplier Part Number | 25777-25 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/25777m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 25 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 3387-41-5 |