We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Kpt-185; Purity- Greater Than Or Equal To 98%; Size- 25 Mg
Cayman Kpt-185; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$283.50
Your Price
$283.50
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-26074-25 |
| MFG.PART: | 26074-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
KPT-185 is an inhibitor of Exportin 1 (XPO1/CRM1) with anticancer activity.1,2 It reduces proliferation in a panel of patient-derived acute myeloid leukemia cells (IC50s = 100-500 nM).1 KPT-185 induces cell cycle arrest in the G1 phase and apoptosis in MOLT-4 T cell acute lymphoblastic leukemia cells and in a panel of six non-small cell lung cancer (NSCLC) cell lines in a time- and dose-dependent manner.2,3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-[3-
CAS Number
1333151-73-7
Molecular Formula
C16H16F3N3O3
Formula Weight
355.3
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: 15 mg/ml
λmax
233, 278 nm
SMILES
COC1=CC(C2=NN(/C=C\C(OC(C)C)=O)C=N2)=CC(C(F)(F)F)=C1
InChi Code
InChI=1S/C16H16F3N3O3/c1-10(2)25-14(23)4-5-22-9-20-15(21-22)11-6-12(16(17,18)19)8-13(7-11)24-3/h4-10H,1-3H3/b5-4-
InChi Key
NLNGWFLRRRYNIL-PLNGDYQASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-26074-25 |
|---|---|
| Supplier Part Number | 26074-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/26074m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 1333151-73-7 |