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Cayman Cox-1 (Human, Recombinant; Mammalian Expressed); 5 Kunits; ≥80% Estimated By Sds-Page
Cayman Cox-1 (Human, Recombinant; Mammalian Expressed); 5 Kunits; ≥80% Estimated By Sds-Page - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$820.00
Your Price
$820.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-26306-5 |
MFG.PART: | 26306-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
GW 803430 is an antagonist of melanin-concentrating hormone receptor 1 (MCH1; IC50 = 0.5 nM). It reduces cumulative body weight and food intake in diet-induced obese rats when administered at doses of 1 and 3 mg/kg. GW 803430 (10 and 30 mg/kg) decreases marble-burying behavior in mice, indicating anxiolytic activity, but does not affect performance in the rotorod test. It also reduces immobility time in the forced swim and tail suspension tests in mice at doses of 3 and 10 mg/kg, respectively, indicating antidepressant-like activity.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-(4-chloro phenyl)-3-[3- methoxy-4-[2- (1-pyrrol idinyl)ethoxy] phenyl]-thieno [3,2-d]pyrim idin-4(3H)-one
CAS Number
515141-51-2
Synonyms
- GW 3430
Molecular Formula
C25H24ClN3O3S
Formula Weight
482.0
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 2 mg/ml
- DMSO: 2 mg/ml
- Ethanol: 2 mg/ml
- PBS (pH 7.2): Slightly soluble
λmax
228, 264, 312 nm
SMILES
O=C1C2=C(C=C(C3=CC=C(Cl)C=C3)S2)N=CN1C4=CC(OC)=C(OCCN5CCCC5)C=C4
InChi Code
InChI=1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3
InChi Key
MWULMTACIBZPGN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-26306-5 |
---|---|
Supplier Part Number | 26306-5 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
Temperature | -80 |
Refrigerated-Frozen | Frozen |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |