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Cayman Fam-Amyloid- Beta (1-40) Peptide (Human) (Trifluoroacetate
Cayman Fam-Amyloid- Beta (1-40) Peptide (Human) (Trifluoroacetate Salt); Purity- Greater Than Or Equal To 95%; Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$479.00
Your Price
$479.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-27412-500 |
| MFG.PART: | 27412-500 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Olopatadine-d3 is intended for use as an internal standard for the quantification of olopatadine (Item No. ) by GC- or LC-MS. Olopatadine is a histamine H1 receptor antagonist (Ki =41 nM). It is 1,059- and 4,177-fold selective for histamine H1 over H2 and H3 receptors, respectively. Olopatadine inhibits histamine-induced phosphoinositide turnover in isolated human conjunctival epithelial cells, isolated human corneal fibroblasts, and human trabecular meshwork (TM3) cells (IC50s = 9.5, 19, and 39.9 nM, respectively). In vivo, olopatadine inhibits passive cutaneous anaphylaxis in rats (ED50 = 49 µg/kg) and IgG1-mediated bronchoconstriction in ovalbumin-sensitized guinea pigs (ED50 = 30 µg/kg). Formulations containing olopatadine have been used in the treatment of allergic rhinitis and conjunctivitis, as well as in the treatment of itch in patients with well-controlled urticaria.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
11Z-[3-
CAS Number
1331635-21-2
Molecular Formula
C21H20D3NO3 • HCl
Formula Weight
376.9
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility
- Methanol: Slightly soluble
- Water: Slightly soluble
SMILES
[2H]C([2H])([2H])N(C)CC/C=C1C2=CC(CC(O)=O)=CC=C2OCC3=CC=CC=C3/1.Cl
InChi Code
InChI=1S/C21H23NO3.ClH/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24;/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24);1H/b18-8+;/i1D3;
InChi Key
HVRLZEKDTUEKQH-KSSVLRJGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-27412-500 |
|---|---|
| Supplier Part Number | 27412-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/27412m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |