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Cayman Trihexyphenidyl (Hydrochloride); Purity- Greater Than Or E
Cayman Trihexyphenidyl (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 500 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$32.00
Your Price
$32.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-27643-500 |
| MFG.PART: | 27643-500 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Trihexyphenidyl is an antagonist of M1 muscarinic acetylcholine receptors.1 It binds to rat M1 receptors in cerebral cortex selectively over rat M2 receptors in heart tissue (IC50s = 3.7 and 31 nM, respectively). Trihexyphenidyl inhibits contractions induced by acetylcholine (Item No. 23829) in guinea pig ileum (IC50 = 22 nM).2 It also inhibits oxotremorine-induced tremors and physostigmine-induced mortality in mice (ED50s = 2 and 3.6 mg/kg, respectively). Trihexyphenidyl (20 mg/kg) improves abnormal movement in a mouse model of L-3,4-dihydroxyphenylalanine (L-DOPA) responsive dystonia (DRD) that expresses mutant tyrosine hydroxylase (TH).3 Formulations containing trihexyphenidyl have been used in the symptomatic treatment of Parkinsons disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
α-cyclohexyl-
CAS Number
52-49-3
Synonyms
- Benzhexol hydrochloride
Molecular Formula
C20H31NO • HCl
Formula Weight
337.9
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 2 mg/ml
- DMSO: 2 mg/ml
- Ethanol: 3 mg/ml
- Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
SMILES
OC(CCN1CCCCC1)(C2=CC=CC=C2)C3CCCCC3.Cl
InChi Code
InChI=1S/C20H31NO.ClH/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;1H
InChi Key
QDWJJTJNXAKQKD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-27643-500 |
|---|---|
| Supplier Part Number | 27643-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/27643m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 52-49-3 |