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Cayman Antibiotic Pf 1052; Purity- Greater Than Or Equal To 95%;
NETA PART: | CAYM-27743-1 |
MFG.PART: | 27743-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
SRI-011381 is an activator of TGF-β signaling. It reduces increases in cell death and the number of dystrophic neurites induced by amyloid-β (1-42) (Aβ42; Item No. ) in primary mouse embryonic forebrain neurons when used at a concentration of 3 µM. SRI-011381 (2 and 5 µM) increases phagocytosis of Aβ42 by greater than 20% in J774A.1 and THP-1 macrophages. It increases contextual fear conditioning freezing time and spontaneous alternations in the Y-maze, indicating prevention of memory deficits, in the APP751Lon,Swe transgenic mouse model of Alzheimer’s disease when administered at a dose of 10 mg/kg for 10 weeks.
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 15 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 25 mg/ml
- Ethanol:PBS (pH 7.2) (1:4): 0.1 mg/ml
Shipping & Storage Information
SKU | CAYM-27743-1 |
---|---|
Supplier Part Number | 27743-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/27743m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | JP |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 147317-15-5 |