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Cayman Sch 527123; Purity- Greater Than Or Equal To 98%; Size- 1
NETA PART: | CAYM-27800-1 |
MFG.PART: | 27800-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
FG-7142 is a benzodiazepine receptor ligand with anxiogenic and proconvulsant properties. It increases benzodiazepine receptor ligand binding and GABA-dependent chloride uptake in primary chick cerebral cortical neurons when used at a concentration of 1 μM. FG-7142 (5 mg/kg) decreases pinning of the other animal and increases avoiding behavior in rats, an effect that can be prevented by the benzodiazepine receptor antagonist Ro 15-1788 (flumazenil; Item No. ). It reduces the infused pentylenetetrazol (PTZ; Item No. ) seizure threshold and induces generalized seizures in mice when administered at doses of 10 and 40 mg/kg, respectively. FG-7142 (3.75, 7.5, and 15 mg/kg, i.p.) also decreases food and water intake, eating rate, and time spent in the open arms of the elevated plus maze in female rats.
WARNING This product is not for human or veterinary use.
Technical Information
- ZK 39106
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- Ethanol: 1 mg/ml
Shipping & Storage Information
SKU | CAYM-27800-1 |
---|---|
Supplier Part Number | 27800-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/27800m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 473727-83-2 |