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Cayman 3-Hydroxy Darifenacin; Purity- Greater Than Or Equal To 95
NETA PART: | CAYM-27852-1 |
MFG.PART: | 27852-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine (Item No. )., Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporated into the DNA., Ara-G inhibits DNA replication by 92% after 30 minutes when used at a concentration of 50 µM in CEM cells, which are used as a model for human T lymphoblasts. It also halts the cell cycle at the sub-G1 phase and induces apoptosis in CEM cells. Syngeneic bone marrow containing 6C3HED tumor cells treated with ara-G (100 mM) ex vivo prior to transplantation increases survival of lethally irradiated mice and induces reconstitution of lymphoid, myeloid, and erythroid cell linages.
WARNING This product is not for human or veterinary use.
Technical Information
- ara-Guanosine
- Guanine Arabinoside
- NSC 76352
- DMF: 3 mg/ml
- DMSO: 5 mg/ml
- Ethanol: Partially soluble
- PBS (pH 7.2): 0.3 mg/ml
Shipping & Storage Information
SKU | CAYM-27852-1 |
---|---|
Supplier Part Number | 27852-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/27852m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CA |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 206048-82-0 |