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Cayman Z-Phe-Tyr(Tbu)-Diazomethylketone; Purity- Greater Than Or
Cayman Z-Phe-Tyr(Tbu)-Diazomethylketone; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$257.00
Your Price
$257.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-27877-10 |
| MFG.PART: | 27877-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Z-Phe-Tyr(tBu)-diazomethylketone is an inhibitor of cathepsin L (Kinact = 200,000 M-1s-1).1,2 It is selective for cathepsin L over cathepsin S and cathepsin B (Kinacts = 30 and 10.3 M-1s-1, respectively). Z-Phe-Tyr(tBu)-diazomethylketone is active against bloodstream forms of T. brucei brucei clone 427-221a in vitro (EC50 = 126 μM).3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(1S)-2-
CAS Number
114014-15-2
Synonyms
- Cbz-Phe-Tyr(O-t-Bu)-CHN2
- Z-Phe-Tyr(tBu)-CHN2
Molecular Formula
C31H34N4O5
Formula Weight
542.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- Ethyl Acetate: 10 mg/ml
λmax
254 nm
SMILES
O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(C=[N+]=[N-])=O)CC2=CC=C(OC(C)(C)C)C=C2)=O)OCC3=CC=CC=C3
InChi Code
InChI=1S/C31H34N4O5/c1-31(2,3)40-25-16-14-23(15-17-25)18-26(28(36)20-33-32)34-29(37)27(19-22-10-6-4-7-11-22)35-30(38)39-21-24-12-8-5-9-13-24/h4-17,20,26-27H,18-19,21H2,1-3H3,(H,34,37)(H,35,38)/t26-,27-/m0/s1
InChi Key
CGONKNHDBTYOOC-SVBPBHIXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-27877-10 |
|---|---|
| Supplier Part Number | 27877-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/27877m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 114014-15-2 |