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Cayman N-Oleoyl-L-Phenylalanine; Purity- Greater Than Or Equal To
![](https://netam2po.netascientific.info/media/skin/seal2.png)
![](https://netam2po.netascientific.info/media/skin/seal.png)
NETA PART: | CAYM-28921-10 |
MFG.PART: | 28921-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
(S)-Flurbiprofen is the COX-active enantiomer of the non-selective COX inhibitor flurbiprofen (Item No. ) with IC50 values of 0.48 and 0.47 µM for COX-1 and COX-2, respectively, in guinea pig whole blood. It inhibits the release of 6-keto prostaglandin F1α (6-keto-PGF1α; Item No. ) and thromboxane B2 (TXB2; Item No. ) from rat whole blood, gastric mucosa, lung, and jejunal tissue ex vivo in a dose-dependent manner. (S)-Flurbiprofen (1 nM) inhibits basal and bradykinin-, serotonin-, and histamine-stimulated prostaglandin E2 (PGE2) release from isolated skin flaps of rat lower hind paws. It also inhibits release of the neuroinflammatory marker calcitonin gene-related peptide (CGRP; Item Nos. | | ) when used at a concentration of 1 μM. In vivo, (S)-flurbiprofen reduces the number of flinches per minute in the formalin test in rats, indicating antinociceptive activity.
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 25 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 25 mg/ml
- PBS (pH 7.2): 0.9 mg/ml
Shipping & Storage Information
SKU | CAYM-28921-10 |
---|---|
Supplier Part Number | 28921-10 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/28921m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 136560-78-6 |